實驗室網頁

姓名:李伯訓

現職:

台大醫院牙科部牙體復形美容牙科主治醫師

國立台灣大學牙醫專業學院口腔生物科學研究所副教授

學歷:

民國83  國立台灣大學牙醫學系  學士

民國85  國立台灣大學牙醫科學研究所  碩士

民國91  國立台灣大學臨床牙醫學研究所  博士

經歷:

UCLA, Mechanical & Aerospace Engineering博士後研究員

中原大學化學工程系博士後研究員

日本國立東北大學齒學部第一保存科研究員

主要研究領域

1.      骨組織工程

2. 薄膜藥物釋放與奈米顆粒

3. 牙科材料研發

專題研究計畫

1. 應用多立面倍半矽氧烷寡聚體/玻璃纖維紗束/樹脂複合材研發根管釘柱以強化牙齒強度及其生物相容性之研究(NSC: 97.8.198.7.31)

2. 應用奈米碳管/無機填料/樹脂複合材以研發根管釘柱及其生物相容性之研究(NSC: 96.8.197.7.31)

3. 預防齲齒含氟貼片的研發 (NTUH: 96.1.1~96.12.31)

4. 二極體雷射穿透不同牙本質厚度後對鏈球菌之殺菌效果 (NSC: 95.8.196.7.31)

5. 牙本質知覺過敏症治療材料之研發 (NTUH: 95.1.1~95.12.31)

6. 氫氧磷灰石應用於齒槽骨組織工程及其與細胞之交互作用NSC: 94.8.195.7.31

7. 研發齲齒預防用之釋氟薄膜 (NSC: 93.8.194.7.31)

期刊論文

1.     Lee BS, Lai EH, Liao KH, Lee CY, Hsieh KH, Lin CP. A novel polyurethane-based root canal obturation material and urethane-acrylate-based root canal sealer. Part II: Evaluation of push-out bond strength. Journal of Endodontics 2008;34:594-598. (SCI)

2.     Hsieh KH, Liao KH, Lai EH, Lee BS, Lee CY, Lin CP. A novel polyurethane-based root canal obturation material and urethane-acrylate-based root canal sealer. Part I: Synthesis and evaluation of mechanical and thermal properties. Journal of Endodontics 2008;34:303-305. (SCI)

3.     Wang YL, Lee BS, Tseng CL, Lin FH, Lin CP. In vitro study of root fracture treated by CO2 laser and DP-bioactive glass paste. Journal of the Formosan Medical Association 2008;107:46-53. (SCI)

4.     Lee BS, Huang SH, Chiang YC, Chien YS, Mou CY, Lin CP. Development of in vitro tooth staining model and usage of catalysts to elevate the effectiveness of tooth bleaching. Dental Materials 2008;24:57-66. (SCI)

5.     Chiang YC, Lee BS, Wang YL, Cheng YA, Chen YL, Shiau JS, Wang DM, Lin CP. Microstructural changes of enamel, dentin-enamel junction, and dentin induced by irradiating outer enamel surfaces with CO2 laser. Lasers in Medical Science 2008;23:41-48. (SCI)

6.     Lee BS, Chen RS, Wang DM, Lai JY, Lin CP. Attachment of MG-63 cells on an RGDS-immobilized asymmetrical polycaprolactone membrane. Journal of Dental Sciences 2007;2:201-210.

7.     Tseng WY, Chen MH, Lu HH, Lin CW, Hsieh TT, Chen CH, Lai JY, Lee BS. Tensile bond strength of Er,Cr:YSGG laser-irradiated human dentin to composite inlays with two resin cements. Dental Materials Journal 2007;26:746-755.

8.     Wang YL, Lee BS, Chang KC, Chiu HC, Lin FH, Lin CP. Characterization, fluoride release and recharge properties of polymer-kaolinite nanocomposite resins. Composites Science and Technology 2007;67:3409-3416. (SCI)

9.     Lee BS, Lin PY, Chen MH, Hsieh TT, Lin CP, Lai JY, Lan WH. Tensile bond strength of Er,Cr:YSGG laser-irradiated human dentin and analysis of dentin-resin interface. Dental Materials 2007;23:570-578. (SCI)

10.  Kuo TC, Lee BS, Kang SH, Lin FH, Lin CP. Cytotoxicity of DP-bioglass paste used for treatment of dentin hypersensitivity. Journal of Endodontics 2007;33:451-454. (SCI)

11.  Lin CY, Lee BS, Liao CC, Cheng WJ, Chang FM, Chen MH. Transdifferentiation of bone marrow stem cells into acinar cells using a double chamber system. Journal of the Formosan Medical Association 2007;106:1-7. (SCI)

12.  Lee BS, Chiang YC, Hung WC, Cheng JH, Lin CP. Failure criteria of dentin-resin adhesion—the J-integral approach. Scripta Materialia 2007;56:863-866. (SCI)

13.  Lee BS, Kang SH, Wang YL, Lin FH, Lin CP. In Vitro Study of Dentinal Tubule Occlusion with Sol-gel DP-bioglass for Treatment of Dentin Hypersensitivity. Dental Materials Journal 2007;26:52-61.

14.  Lin CY, Lee BS, Lee MS, Chen MH. Patients with discolored and malaligned anterior teeth able to obtain significant esthetic improvement after restoration with CAD/CAM (Cerec 3D) porcelain veneers—case report. J Dent Sci 2006;1:88-93.

15.  Lee BS, Lin YW, Chia JS, Hsieh TT, Chen MH, Lin CP, Lan WH. Bactericidal effects of diode laser on Streptococcus mutans after irradiation through different thicknesses of dentin. Lasers in Surgery and Medicine 2006;38:62-69. (SCI)

16.  Chen WP, Lee BS, Chiang YC, Lan WH, Lin CP. Effects of various periodontal ligament elastic moduli on the stress distribution of a central incisor and surrounding alveolar bone. Journal of the Formosan Medical Association 2005;104:830-8. (SCI)

17.  Lee BS, Tsai HY, Tsai YL, Lan WH, Lin CP. In Vitro study of DP-bioglass paste for treatment of dentin hypersensitivity. Dental Materials Journal 2005;24:562-569. (SCI)

18.  Chen WP, Lee BS, Lin CP. Three-dimensional finite element modeling of a maxillary two-rooted premolar—stress analysis with or without modeling of the periodontium. Chin Dent J 2005;24:35-44.

19.  Lee BS, Chang CW, Chen WP, Lan WH, Lin CP. In vitro study of dentin hypersensitivity treated by Nd:YAP laser and bioglass. Dental Materials 2005; ;21:511-519.(SCI)

20.  王若松, 李伯訓, 許耀仁, 林俊彬, 藍萬烘. 不同參數對Er,Cr:YSGG雷射切削人類牙本質效率之比較. 台灣醫學 Formosan J Med 2004;8:467-75.

21.  王若松, 溫秉翰, 李伯訓, 林俊彬, 藍萬烘. Nd:YAP雷射移除根管壁塗抹層之效果. 台灣醫學 Formosan J Med 2004;8:332-8.

22.  Lee BS, Lin CP, Hung YL, Lan WH. Structural changes of Er:YAG laser-irradiated human dentin. Photomedicine and Laser Surgery 2004;22:330-334. (SCI)

23.  Lee BS, Jeng JH, Lin CP, Shoji S, Lan WH. Thermal effect induced by Er:YAG laser with two kinds of fiber tips to enlarge the root canals. Photomedicine and Laser Surgery 2004;22:191-197. (SCI)

24.  Lan WH, Lee BS, Liu HC, Lin CP. Morphological study of Nd:YAG laser usage in treatment of dentinal hypersensitivity. Journal of Endodontics 2004;30:131-134. (SCI)

25.  Lee BS, Hsieh TT, Chi DCH, Lan WH, Lin CP. The role of organic tissue on the punch shear strength of human dentin. Journal of Dentistry 2004;32:101-107. (SCI)

26.  Lee YL, Lee BS, Lin FH, Lin AY, Lan WH, Lin CP. Effects of physiological environments on the hydration behavior of mineral trioxide aggregate. Biomaterials 2004;25:787-793. (SCI)

27.  Lee BS, Lin CP, Lin FH, Li UM, Lan WH. Effect of Nd:YAG Laser Irradiation on the Hardness and Elastic Modulus of Human Dentin. Journal of Clinical Laser Medicine & Surgery 2003;21(1):41-46. (SCI)

28.  Lee BS, Hsieh TT, Lee YL, Lan WH, Hsu YJ, Wen PH, Lin CP. Bond strengths of orthodontic bracket after acid-etched, Er:YAG laser-irradiated, and combined treatment on enamel surface. Angle Orthodontist 2003;73:565-570. (SCI)

29.  黃智嘉, 王若松, 李伯訓, 林思洸, 鄭景暉, 林俊彬, 藍萬烘. 鉺雅鉻雷射對於牙本質表面塗抹層之作用分析. 中華牙誌 2003;22(1):19-28.

30.  石進財, 鄭景暉, 王若松, 李伯訓, 藍萬烘. 根管充填後疼痛因素之探討. 台灣醫學 Formosan J Med 2002;6:552-8.

31.  Li UM, Lee BS, Shih CT, Lan WH, Lin CP. Cyclic fatigue of endodontic nickel titanium rotary instruments: static and dynamic tests. Journal of Endodontics 2002;28:448-452. (SCI)

32.  Lee BS, Lin CP, Lin FH, Lan WH. Ultrastructural changes of human dentin after irradiation by Nd:YAG laser. Lasers in Surgery and Medicine 2002;30:246-252. (SCI)

33.  Lin CP, Lee BS, Lin FH, Kok SH, Lan WH. Phase, compositional, and morphological changes of human dentin after Nd:YAG laser treatment. Journal of Endodontics 2001;27:389-393. (SCI)

34.  Lin CP, Lee BS, Kok SH, Lan WH, Tseng YC, Lin FH. Treatment of tooth fracture by medium energy CO2 laser and DP-bioactive glass paste: Thermal behavior and phase transformation of human tooth enamel and dentin after irradiation by CO2 laser. Journal of Materials Science: Materials in Medicine 2000;11:373-381. (SCI)

35.  Chen YJ, Jeng JH, Lee BS, Chang HF, Chen KC, Lan WH. Effects of Nd:YAG laser irradiation on cultured human gingival fibroblasts. Lasers in Surgery and Medicine 2000;27:471-478. (SCI)

36.  褚文煌, 李伯訓, 鄭琇月, 林俊彬, 陳瑞松, 藍萬烘. 次氯酸鈉對人類牙本質斷裂強度之影響. 中華牙誌1998;17(2):79-85.

聯絡方式:

地址:北市常德街一號台大醫院牙科 

電話:(02) 23123456 ext 62342

E -mailleebs@ntu.edu.tw

台大牙醫學系暨臨床牙醫學研究所網頁-師長簡介英文內容格式

 

Name: Bor-Shiunn Lee

Position:

Attending staff of Restorative and Esthetic Dentistry, Department of Dentistry, National Taiwan University Hospital

Associate Professor, School of Dentistry, College of Medicine, National Taiwan University

Education:(必填)[ 格式:西元畢業年度  學位  畢業學校]

1994  DDS, National Taiwan University

1996  MS, National Taiwan University

2002  PhD, National Taiwan University

Professional Experience:

2004.2~2007.7  Assistant Professor, School of Dentistry, College of Medicine, National Taiwan University

2003.11~2004.1  Postdoctoral researcher, Mechanical & Aerospace Engineering, UCLA

2002.8~2003.10  Postdoctoral researcher, Department of Chemical Engineering, Chung Yuan University

1999.4~2001.3   Researcher, Periodontology and Endodontology, Tohoku University School of Dentistry

Research – A. Research Interests(必填)

1. Interaction between laser and hard tissues
2.  Analysis and strength measurement of materials
3. Crystalline structure of teeth
4. Development of bone composite material
5. Development of dental membrane material

Research – B. International Cooperation

1.      Prof. Chih-Ming Ho, Mechanical & Aerospace Engineering, UCLA

2.      Prof. Hidetoshi Shimauchi, Periodontology and Endodontology, Tohoku University School of Dentistry

Research – C. Grant Support

1.      Development of fluoride-releasing membrane for caries prevention (NSC: 2004.8.12005.7.31)

2.      Application of hydroxyapatite in alveolar bone tissue engineering and cell-hydroxyapatite interactionNSC: 2005.8.12006.7.31

3.      Invention of therapeutic material for treating dentin hypersensitivity (NTUH: 95.1.1~95.12.31)

4.      Bactericidal effects of diode laser on Streptococcus mutans after irradiation through different thickness of dentin (NSC: 95.8.196.7.31)

5.        Research and Development of Fluoride Strips for Prophylaxis of Dental Caries (NTUH: 96.1.1~96.12.31)

6.      Application of carbon nanotube/inorganic filler/resin composite system to develop post for root canal and research on biocompatibility of post  (NSC: 96.8.197.7.31)

Selected Publications- Journal Papers *:

 

1.      Wang YL, Lee BS, Tseng CL, Lin FH, Lin CP. In vitro study of root fracture treated by CO2 laser and DP-bioactive glass paste. Journal of the Formosan Medical Association (accepted)(SCI)

2.      Chiang YC, Lee BS, Wang YL, Cheng YA, Chen YL, Shiau JS, Wang DM, Lin CP. Microstructural changes of enamel, dentin-enamel junction, and dentin induced by irradiating outer enamel surfaces with CO2 laser. Lasers in Medical Science 2007 (In press)(SCI)

3.      Lee BS, Huang SH, Chiang YC, Chien YS, Mou CY, Lin CP. Development of in vitro tooth staining model and usage of catalysts to elevate the effectiveness of tooth bleaching. Dental Materials 2007 (In press)(SCI)

4.      Wang YL, Lee BS, Chang KC, Chiu HC, Lin FH, Lin CP. Characterization, fluoride release and recharge properties of polymer-kaolinite nanocomposite resins. Composites Science and Technology 2007;67:3409-3416. (SCI)

5.      Tseng WY, Chen MH, Lu HH, Lin CW, Hsieh TT, Chen CH, Lai JY, Lee BS. Tensile bond strength of Er,Cr:YSGG laser-irradiated human dentin to composite inlays with two resin cements. Dental Materials Journal 2007;26:746-755.

6.      Kuo TC, Lee BS, Kang SH, Lin FH, Lin CP. Cytotoxicity of DP-bioglass paste used for treatment of dentin hypersensitivity. Journal of Endodontics 2007;33:451-454. (SCI)

7.      Lin CY, Lee BS, Liao CC, Cheng WJ, Chang FM, Chen MH. Transdifferentiation of bone marrow stem cells into acinar cells using a double chamber system. Journal of the Formosan Medical Association 2007;106:1-7. (SCI)

8.      Lee BS, Chiang YC, Hung WC, Cheng JH, Lin CP. Failure criteria of dentin-resin adhesion—the J-integral approach. Scripta Materialia 2007;56:863-866. (SCI)

9.      Lee BS, Kang SH, Wang YL, Lin FH, Lin CP. In Vitro Study of Dentinal Tubule Occlusion with Sol-gel DP-bioglass for Treatment of Dentin Hypersensitivity. Dental Materials Journal 2007;26:52-61. (SCI)

10.  Lee BS, Lin PY, Chen MH, Hsieh TT, Lin CP, Lai JY, Lan WH. Tensile bond strength of Er,Cr:YSGG laser-irradiated human dentin and analysis of dentin-resin interface. Dental Materials 2007;23:570-578. (SCI)

11.  Lin CY, Lee BS, Lee MS, Chen MH. Patients with discolored and malaligned anterior teeth able to obtain significant esthetic improvement after restoration with CAD/CAM (Cerec 3D) porcelain veneers—case report. J Dent Sci 2006;1:88-93.

12.  Lee BS, Lin YW, Chia JS, Hsieh TT, Chen MH, Lin CP, Lan WH. Bactericidal effects of diode laser on Streptococcus mutans after irradiation through different thicknesses of dentin. Lasers in Surgery and Medicine 2006;38:62-69. (SCI)

13.  Chen WP, Lee BS, Chiang YC, Lan WH, Lin CP. Effects of various periodontal ligament elastic moduli on the stress distribution of a central incisor and surrounding alveolar bone. Journal of the Formosan Medical Association 2005;104:830-8. (SCI)

14.  Lee BS, Tsai HY, Tsai YL, Lan WH, Lin CP. In Vitro study of DP-bioglass paste for treatment of dentin hypersensitivity. Dental Materials Journal 2005;24:562-569. (SCI)

15.  Chen WP, Lee BS, Lin CP. Three-dimensional finite element modeling of a maxillary two-rooted premolar—stress analysis with or without modeling of the periodontium. Chin Dent J 2005;24:35-44.

16.  Lee BS, Chang CW, Chen WP, Lan WH, Lin CP. In vitro study of dentin hypersensitivity treated by Nd:YAP laser and bioglass. Dental Materials 2005; ;21:511-519.(SCI)

17.  王若松, 李伯訓, 許耀仁, 林俊彬, 藍萬烘. 不同參數對Er,Cr:YSGG雷射切削人類牙本質效率之比較. 台灣醫學 Formosan J Med 2004;8:467-75.

18.  王若松, 溫秉翰, 李伯訓, 林俊彬, 藍萬烘. Nd:YAP雷射移除根管壁塗抹層之效果. 台灣醫學 Formosan J Med 2004;8:332-8.

19.  Lee BS, Lin CP, Hung YL, Lan WH. Structural changes of Er:YAG laser-irradiated human dentin. Photomedicine and Laser Surgery 2004;22:330-334. (SCI)

20.  Lee BS, Jeng JH, Lin CP, Shoji S, Lan WH. Thermal effect induced by Er:YAG laser with two kinds of fiber tips to enlarge the root canals. Photomedicine and Laser Surgery 2004;22:191-197. (SCI)

21.  Lan WH, Lee BS, Liu HC, Lin CP. Morphological study of Nd:YAG laser usage in treatment of dentinal hypersensitivity. Journal of Endodontics 2004;30:131-134. (SCI)

22.  Lee BS, Hsieh TT, Chi DCH, Lan WH, Lin CP. The role of organic tissue on the punch shear strength of human dentin. Journal of Dentistry 2004;32:101-107. (SCI)

23.  Lee YL, Lee BS, Lin FH, Lin AY, Lan WH, Lin CP. Effects of physiological environments on the hydration behavior of mineral trioxide aggregate. Biomaterials 2004;25:787-793. (SCI)

24.  Lee BS, Lin CP, Lin FH, Li UM, Lan WH. Effect of Nd:YAG Laser Irradiation on the Hardness and Elastic Modulus of Human Dentin. Journal of Clinical Laser Medicine & Surgery 2003;21(1):41-46. (SCI)

25.  Lee BS, Hsieh TT, Lee YL, Lan WH, Hsu YJ, Wen PH, Lin CP. Bond strengths of orthodontic bracket after acid-etched, Er:YAG laser-irradiated, and combined treatment on enamel surface. Angle Orthodontist 2003;73:565-570. (SCI)

26.  黃智嘉, 王若松, 李伯訓, 林思洸, 鄭景暉, 林俊彬, 藍萬烘. 鉺雅鉻雷射對於牙本質表面塗抹層之作用分析. 中華牙誌 2003;22(1):19-28.

27.  石進財, 鄭景暉, 王若松, 李伯訓, 藍萬烘. 根管充填後疼痛因素之探討. 台灣醫學 Formosan J Med 2002;6:552-8.

28.  Li UM, Lee BS, Shih CT, Lan WH, Lin CP. Cyclic fatigue of endodontic nickel titanium rotary instruments: static and dynamic tests. Journal of Endodontics 2002;28:448-452. (SCI)

29.  Lee BS, Lin CP, Lin FH, Lan WH. Ultrastructural changes of human dentin after irradiation by Nd:YAG laser. Lasers in Surgery and Medicine 2002;30:246-252. (SCI)

30.  Lin CP, Lee BS, Lin FH, Kok SH, Lan WH. Phase, compositional, and morphological changes of human dentin after Nd:YAG laser treatment. Journal of Endodontics 2001;27:389-393. (SCI)

31.  Lin CP, Lee BS, Kok SH, Lan WH, Tseng YC, Lin FH. Treatment of tooth fracture by medium energy CO2 laser and DP-bioactive glass paste: Thermal behavior and phase transformation of human tooth enamel and dentin after irradiation by CO2 laser. Journal of Materials Science: Materials in Medicine 2000;11:373-381. (SCI)

32.  Chen YJ, Jeng JH, Lee BS, Chang HF, Chen KC, Lan WH. Effects of Nd:YAG laser irradiation on cultured human gingival fibroblasts. Lasers in Surgery and Medicine 2000;27:471-478. (SCI)

33.  褚文煌, 李伯訓, 鄭琇月, 林俊彬, 陳瑞松, 藍萬烘. 次氯酸鈉對人類牙本質斷裂強度之影響. 中華牙誌1998;17(2):79-85.

Selected Publications- Conference Papers:

1.      Huang SH, Lee BS, Chen HJ, Lin CP. Development of in vitro tooth staining model for tooth bleaching. IADR, 2007, New Orleans, USA.

2.      陳虹君, 李伯訓, 林俊彬. 第二類牙中牙上顎側門齒根管治療病例報告.中華牙醫學會2006.

3.      曾筱婷, 李伯訓, 藍萬烘. 奈米碳管/樹脂複合材料應用於牙科根管內釘柱材料的研究. 中華牙醫學會2006.

4.      賴易廷, 李伯訓, 林思洸, 藍萬烘. sOGP10~14接枝於聚己內酯多元醇-氫氧基磷灰石複合薄膜對於成骨細胞活性之研究. 中華牙醫學會2006.

5.      Lee BS, Lin YW, Chia JS, Hsieh TT, Chen MH, Lin CP, Lan WH. Bactericidal effects of diode laser on Streptococcus mutans after irradiation through different thicknesses of dentin. 10th International Congress on Lasers in Dentistry 2006, Berlin, Germany.

6.      Lin CP, Lee BS, Chen YL, Lan WH. Thermal effect of CO2 laser on the microstructures of tooth. IADR, 2004, Hawaii.

7.      Lee BS, Wang DM, Lan WH, Lin CP, Lai JY. Polycaprolactone biodegradable membrane for guide tissue regeneration. The Third Conference on Membrane Science & Technology in Taiwan. 2003, Chungli, Taiwan.

8.      Lee BS, Lan WH. Compositional and morphological changes of human dentin after Er:YAG laser irradiation. 8th International Congress on Lasers in Dentistry 2002, Yokohama, Japan.

9.      Lee BS, Shoji S, Nemoto M, Ooishi J, Okagami Y, Kataoka K, Horiuchi H. Thermal behaviors of root canal after Er:YAG laser irradiation. 7th International Congress on Lasers in Dentistry 2000, Brussels, Belgium.

10.  Lee BS, Tseng YC, Lin FH, Lin CP, Lan WH. The interaction of CO2 laser irradiation on enamel, dentine, and bioglass. 6th International Congress on Lasers in Dentistry 1998, Maui, Hawaii, USA.

11.  李伯訓. 牙本質、牙釉質及DP-bioactive-glassCO2雷射照射後之相轉變及再結晶分析. 中華牙醫學會1998.

12.  李伯訓. 次氯酸鈉和EDTA對牙本質的清創效果低真空掃描電子顯微鏡漸進式觀察. 中華牙醫學會1996.

13.  李伯訓. 根尖囊腫與增殖性骨膜炎病例報告. 中華牙醫學會1995.

Selected Publications- Books:

Lee BS (2002). Effect of Nd:YAG laser irradiation on human dentin. Ph.D. Thesis, National Taiwan University.

Selected Publications- Patents:

 

Contact information:

Address: No. 1, Chang-Te St., Taipei city, Taiwan

Tel: (02) 23123456 ext 7336

Fax: (02) 23821212

E-mail: leebs@ntu.edu.tw