高全良老師

學歷

台大醫事技術學系 理學士

職稱

台大醫事技術學系 副教授
台大醫學院附設醫院檢驗醫學部 兼任副主任

學會

中華民國醫事檢驗學會常務理事
中華民國微生物學會理事
台灣臨床標準協會常務理事
國際醫檢學會理事
美國ASCPi台灣指導委員會委員

Email：chuanliang@ntu.edu.tw

電話：02-23123456轉66903或 66929

老師的話

人生有得必有失，只要對有意義之事努力完成，得必多於失

嗜好

爬山、旅遊

研究主題

1.  Hung JJ, Hsieh MT, Young MJ, Kao CL, King CC, Chang W. An external loop region of domain III of dengue virus type 2 envelope protein is involved in serotype-specific binding to mosquito but not mammalian cells. J Virol 2004 Jan;78:378-88. (SCI)
2.  Yeh SH, Wang HY, Tsai CY, Kao CL, Yang JY, Liu HW, Su IJ, Tsai SF, Chen DS, Chen PJ; National Taiwan University SARS Research Team. Characterization of severe acute respiratory syndrome coronavirus genomes in Taiwan: molecular epidemiology and genome evolution. Proc Natl Acad Sci U S A. 2004 Feb 24;101:2542-7. (SCI)
3.  Hsueh PR, Chen PJ, Hsiao CH, Yeh SH, Cheng WC, Wang JL, Chiang BL, Chang SC, Chang FY, Wong WW, Kao CL*, Yang PC*; SARS Research Group of National Taiwan University College of Medicine and National Taiwan University Hospital Patient data, early SARS epidemic, Taiwan. Emerg Infect Dis. 2004 Mar;10:489-93. (SCI)
4.  Hu JJ, Kao CL, Lee PI, Chen CM, Lee CY, Lu CY, Huang LM. Clinical features of influenza A and B in children and association with myositis. J Microbiol Immunol Infect. 2004 Apr;37:95-8. (SCI)
5.  Chen YC, Chen PJ, Chang SC, Kao CL, Wang SH, Wang LH, Yang PC; SARS Research Group of National Taiwan University College of Medicine and National Taiwan University Hospital. Infection control and SARS transmission among healthcare workers, Taiwan. Emerg Infect Dis. 2004 May;10:895-8. (SCI)
6.  Chang WT, Kao CL, Chung MY, Chen SC, Lin SJ, Chiang WC, Chen SY, Su CP, Hsueh PR, Chen WJ, Chen PJ, Yang PC. SARS exposure and emergency department workers. Emerg Infect Dis. 2004 Jun;10:1117-9. (SCI)
7.  Chen HC, Lai SY, Sung JM, Lee SH, Lin YC, Wang WK, Chen YC, Kao CL, King CC, Wu-Hsieh BA. Lymphocyte activation and hepatic cellular infiltration in immunocompetent mice infected by dengue virus. J Med Virol. 2004 Jul;73:419-31. (SCI)
8.  Wang WK, Chen SY, Liu IJ, Chen YC, Chen HL, Yang CF, Chen PJ, Yeh SH, Kao CL, Huang LM, Hsueh PR, Wang JT, Sheng WH, Fang CT, Hung CC, Hsieh SM, Su CP, Chiang WC, Yang JY, Lin JH, Hsieh SC, Hu HP, Chiang YP, Wang JT, Yang PC, Chang SC; SARS Research Group of the National Taiwan University/National Taiwan University Hospital. Detection of SARS-associated coronavirus in throat wash and saliva in early diagnosis. Emerg Infect Dis 2004 Jul;10(7):1213-9. (SCI)
9.  Liu IJ, Hsueh PR, Lin CT, Chiu CY, Kao CL, Liao MY, Wu HC. Disease-specific B Cell epitopes for serum antibodies from patients with severe acute respiratory syndrome (SARS) and serologic detection of SARS antibodies by epitope-based peptide antigens. J Infect Dis. 2004 Aug 15;190:797-809. (SCI)
10.  Hsueh PR, Kao CL, Lee CN, Chen LK, Ho MS, Sia C, Fang XD, Lynn S, Chang TY, Liu SK, Walfield AM, Wang CY. SARS antibody test for serosurveillance. Emerg Infect Dis. 2004 Sep;10:1558-62. (SCI)
11.  Wang WK, Chen SY, Liu IJ, Kao CL, Chen HL, Chiang BL, Wang JT, Sheng WH, Hsueh PR, Yang CF, Yang PC, Chang SC; Severe Acute Respiratory Syndrome Research Group of the National Taiwan University College of Medicine/NTU Hospital. Temporal relationship of viral load, ribavirin, interleukin (IL)-6, IL-8, and clinical progression in patients with severe acute respiratory syndrome. Clin Infect Dis. 2004 Oct 1;39:1071-5. (SCI)
12.  Chang LY, Huang FY, Wu YC, Su IJ, Chiu NC, Chen KT, Wu HS, Lin TH, Peng SF, Kao CL, Lee CY, Huang LM. Childhood severe acute respiratory syndrome in Taiwan and how to differentiate it from childhood influenza infection. Arch Pediatr Adolesc Med. 2004 Nov;158:1037-42. (SCI)
13.  Hsueh PR, Huang LM, Chen PJ, Kao CL, Yang PC..Chronological evolution of IgM, IgA, IgG and neutralisation antibodies after infection with SARS-associated coronavirus. Clin Microbiol Infect. 2004 Dec;10:1062-6. (SCI)
14.  Kao CL*, King CC, Chao DY, Wu HL, Chang GJ. Laboratory diagnosis of dengue virus infection: current and future perspectives in clinical diagnosis and public health. J Microbiol Immunol Infect. 2005 Feb;38(1):5-16.
15.  Shih SR, Chen GW, Yang CC, Yang WZ, Liu DP, Lin JH, Chiu SC, Chen HY, Tsao KC, Huang HG, Huang YL, Mok CK, Chen CJ, Lin TY, Wang JR, Kao CL, Lin KH, Chen LK, Eng HL, Liu YC, Chen PY, Lin JS, Wang JH, Lin CW, Chan YJ, Lu JJ, Hsiung CA, Pei-Jer Chen PJ, Su IJ. Laboratory-based surveillance and molecular epidemiology of influenza virus in Taiwan. J Clin Microbiol. 2005 Apr;43:1651-61. (SCI)
16.  Shao PL, Hsueh PR, Chang LY, Lu CY, Kao CL, Chiang YP, Huang HY, Huang FY, Lee CY, Chang LJ, Wu TC, Huang LM; SARS Research Group of National Taiwan University College of Medicine; National Taiwan University Hospital. Development of immunoglobulin G enzyme-linked immunosorbent assay for the serodiagnosis of severe acute respiratory syndrome. J Biomed Sci. 2005 Feb;12(1):59-64. (SCI)
17.  Lin S, Lee CK, Lee SY, Kao CL, Lin CW, Wang AB, Hsu SM. Surface ultrastructure of SARS coronavirus revealed by atomic force microscopy. Cell Microbiol. 2005 Dec;7(12):1763-70. (SCI)
18.  Yang TT, Huang LM, Lu CY, Kao CL, Lee WT, Lee PI, Chen CM, Huang FY, Lee CY, Chang LY. Clinical features and factors of unfavorable outcomes for non-polio enterovirus infection of the central nervous system in northern Taiwan, 1994-2003. .J Microbiol Immunol Infect. 2005 Dec;38(6):417-24.
19.  Chang LY, Chiang BL, Kao CL, Wu MH, Chen PJ, Berkhout B, Yang HC, Huang LM; Kawasaki Disease Research Group. Lack of Association between Infection with a Novel Human Coronavirus (HCoV), HCoV-NH, and Kawasaki Disease in Taiwan. J Infect Dis. 2006 Jan 15;193(2):283-6. (SCI)
20.  Lin KH, Hwang KP, Ke GM, Wang CF, Ke LY, Hsu YT, Tung YC , Chu PY, Chen BH, Chen HL , Kao CL, Wang JR, Eng HL, Sheng-Yu Wang SY, Hsu LC  Hour-Young Chen HY.  Evolution of EV71 genogroup in Taiwan from 1998 to 2005: an emerging of subgenogroup C4 of EV71. J Med Virol. 2006 Feb;78(2):254-62. (SCI)
21.  Yen YT, Liao F, Hsiao CH, Kao CL, Chen YC,. Wu-Hsieh BA. Modeling the early events of severe acute respiratory syndrome coronavirus infection in vitro. J Virol. 2006 Mar; 80(6):2684-93. (SCI)
22.  Cheng MF, Chen BC, Kao CL, Kao CH, Hsieh KS, Liu YC. Human metapneumovirus as a causative agent of lower respiratory tract infection in four patients: the first report of human metapneumovirus infection confirmed by RNA sequences in Taiwan. Scand J Infect Dis. 2006 May;38(5):392-6. (SCI)
23.  Lin YP, Chang SY, Kao CL, Huang LM, Chung MY, Yang JY, Chen HY, Taniguchi K, Tsai KS, Lee CN. Molecular epidemiology of G9 rotaviruses in Taiwan between 2000 and 2002. J Clin Microbiol. 2006 Oct ;44(10):3686-94. (SCI)
24.  Chang SY, Sheng WH, Lee CN, Sun HY, Kao CL, Chang SF, Liu WC, Yang JY, Wong WW, Hung CC, Chang SC. Molecular epidemiology of HIV type 1 subtypes in Taiwan: Outbreak of HIV Type 1 CRF07_BC infection in intravenous drug users. AIDS Res Hum Retroviruses. 2006  Nov 22(11):1055-66. (SCI)
25.  Kung CM, King CC, Lee CN, Huang LM, Lee PI, Kao CL.*Differences in replication capacity between enterovirus 71 isolates obtained from patients with encephalitis and those obtained from patients with herpangina in Taiwan. J Med Virol 2007 Jan; 79:60-8. (SCI)
26.  Chan PC, Wang CY, Wu PS, Chang PY, Yang TT, Chiang YP, Kao CL, Chang LY, Lu CY, Lee PI, Chen JM, Shao P L, Fu-Yuan Huang FY, Lee CY, Huang LM. Detection of human metapneumovirus in hospitalized children with acute respiratory tract infection using real-time RT-PCR in a hospital in northern Taiwan. J Formos Med Assoc. 2007 Jan;106 (1):16-24. (SCI)
27.  Chang LY, Lee CY, Kao CL, Fang TY, Lu CY, Lee PI, Huang LM. Hand, foot and mouth disease complicated with central nervous system involvement in Taiwan in 1980-1981. J Formos Med Assoc. 2007 Feb;106:173-6. (SCI)
28.  Lee JT, Chang LY, Wang LC, Kao CL, ShaoPL, Lu CY, LeePI, Chen JM, Lee CY, Huang LM. Epidemiology of respiratory syncytial virus infection in northern Taiwan, 2001-2005 -- seasonality, clinical characteristics, and disease burden. J Microbiol Immunol Infect. 2007 Aug;40(4):293-301.
29.  Chang JB, Wu JL, Tsao KC, Hsieh WS, HuangYY, Shih YL, Chang LF, Kao CL*. Accreditation of medical laboratories by using ISO15189 in Taiwan: A report of fitness investigation. J Biomed Lab Sci 2007; 19: 47-55.
30.  Cheng CC, Huang LM, Kao CL, Lee PI, Chen JM, Lu CY, Lee CY, Chang SY, Chang LY. Molecular and clinical characteristics of adenoviral infections in Taiwanese children in 2004-2005. Eur J Pediatr. 2007 Sep 18; [Epub ahead of print].
31.  Wu PS, Chang LY, Berkhout B L. van der Hoek L, Lu CY, Kao CL, Lee PI, Shao PL, Lee CY, Huang FY, Huang LM. Clinical manifestations of human coronavirus NL63 infection in children in Taiwan. Eur J Pediatr. 2008 Jan; 167(1):75-80. (SCI)
32.  Chang SY, Lee CN*, Lin PH, Huang HH, Chang LY, Ko W, Chang SF, Lee PI, Huang LM, Kao CL*. A community-derived outbreak of adenovirus type 3 in children in Taiwan between 2004 and 2005. J Med Virol. 2008 Jan;80(1):102-12. (SCI)
33. Chao YC, Huang CS, Lee CN, Chang SY, King CC, Kao CL* Higher infection of dengue virus serotype 2 in human monocytes of patients with G6PD deficiency. PLoS ONE. 2008 Feb 13;3(2):e1557
34. Chen CH, Lin YT, Yang YH, Wang LC, Lee JH, Kao CL, Chiang BL. Ribavirin for respiratory syncytial virus bronchiolitis reduced the risk of asthma and allergen sensitization. Pediatr Allergy Immunol. 2008 Mar;19(2):166-72.(SCI)
35. Su CT, Hsu JT, Hsieh HP, Lin PH, Chen TC, Kao CL, Lee CN, Chang SY Anti-HSV activity of digitoxin and its possible mechanisms Antiviral Res. 2008 Jul;79(1):62-70.(SCI)
36. Lin HC, Kao CL, Chang LY, Hsieh YC, Shao PL, Lee PI, Lu CY, Lee CY, Huang LM. Astrovirus gastroenteritis in children in Taipei. J Formos Med Assoc. 2008 Apr;107(4):295-303. (SCI)
37. Lai CY, Tsai WY, Lin SR, Kao CL, Hu HP, King CC, Wu HC, Chang GJ, Wang WK. Antibodies to envelope glycoprotein of dengue virus during the natural course of infection are predominantly cross-reactive and recognize epitopes containing highly conserved residues at the fusion loop of domain II. J Virol. 2008 Jul;82(13):6631-43.(SCI)
38. Lin YP, Kao CL, Chang SY, Taniguchi K, Hung PY, Lin HC, Huang LM, Huang HH, Yang JY, Lee CN.Determination of Human Rotavirus VP6 Genogroups I and II by Reverse Transcription-Polymerase Chain Reaction. J Clin Microbiol. 2008 Oct;46(10):3330-7.(SCI)  
39. Liu IJ, Kao CL, Hsieh SC, Wey MT, Kan LS, Wang WK. Identification of a minimal peptide derived from heptad repeat (HR) 2 of spike protein of SARS-CoV and combination of HR1-derived peptides as fusion inhibitors. Antiviral Res. 2009 Jan;81(1):82-7.(SCI)
40. Tsai YT, Chang SY, Lee CN, Kao CL* .Human TLR3 recognizes dengue virus and modulates viral replication in vitro. Cell Microbiol. 2008 Dec 24. [Epub ahead of print].(SCI)
41. Wu CH, Yeh SH, Tsay YG, Shieh YH, Kao CL, Chen YS, Wang SH, Kuo TJ, Chen DS, Chen PJ. Glycogen Synthase Kinase-3 Regulates the Phosphorylation of Severe Acute Respiratory Syndrome Coronavirus Nucleocapsid Protein and Viral Replication. J Biol Chem. 2009 Feb 20;284(8):5229-5239. (SCI)
42. Chang SY, Ko WS, Kao JT, Chang LY, Sun HY, Chen MY, Hsieh SM, Sheng WH, Chang SF, Liu WC, Wu CH, Hsu HJ, Kao CL, Lee CN, J\Hung CC, Chang SC. Association of Single-Nucleotide Polymorphism 3 and c.553G>T of APOA5 with Hypertriglyceridemia after Treatment with Highly Active Antiretroviral Therapy Containing Protease Inhibitors in HIV-Infected Individuals in Taiwan. Clin Infect Dis. 2009;48(6):832-835.